ME1036, a novel carbapenem, with enhanced activity against clinical isolates causing bacteraemic community-acquired pneumonia.

نویسندگان

  • Ian Morrissey
  • Don Biek
  • Regina Janes
چکیده

fer of such strains from animal to meat products, e.g. during slaughtering. The characterization and comparison of plasmids in this study support the theory of epidemic spread of plasmids being the primary mechanism for dissemination of b-lactamase genes and the existence of a gene reservoir in food products, especially imported food products, that potentially can be transferred via the food chain to humans.

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منابع مشابه

In vitro activities of ME1036 (CP5609), a novel parenteral carbapenem, against methicillin-resistant staphylococci.

ME1036, formerly CP5609, is a novel parenteral carbapenem with a 7-acylated imidazo[5,1-b]thiazole-2-yl group directly attached to the carbapenem moiety of the C-2 position. The present study evaluated the in vitro activities of ME1036 against clinical isolates of gram-positive and gram-negative bacteria. ME1036 displayed broad activity against aerobic gram-positive and gram-negative bacteria. ...

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عنوان ژورنال:
  • The Journal of antimicrobial chemotherapy

دوره 64 1  شماره 

صفحات  -

تاریخ انتشار 2009